You can reply to buyer’s (or bidder’s) question from this listing software.

Your “Unanswered” questions are automatically shown at under of item titles. And input forms for replying and “Respond” buttons are also shown at right of each questions. I’ll add a screen shot soon.

You can reply one by one, just input answer text and click “Respond” button. It’s easy and fast!

Of course if you manage multiple eBay accounts to this listing software, you can reply to all from single screen.